化合物简介
A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
基本信息
中文名称
西他列汀-A
英文名称
3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]p yrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone
中文别名
英文别名
2-Methylontan-1-ol、3-amino-1-(3-trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-4-(2,4,5-trifluoro-phenyl)-butan-1-one、2-methyloctanol、2-methyloctan-1-ol、3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one、4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine、(2RS)-2-methyloctan-1-ol、(R/S)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine、(2RS)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-rifluorophenyl)butan-2-amine、7-(1-oxo-3-amino-4-(2,4,5-trifluorophenyl)butyl)-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine
CAS号
823817-56-7
分子式
C16H15F6N5O
分子量
407.314
精确质量
407.118
PSA
77.04
LOGP
2.6547
物化性质
密度
1.61g/cm3
沸点
529.9ºC at 760 mmHg
闪点
274.3ºC
折射率
1.59
储存条件
Refrigerator
合成路线
共找到1条合成路线 >上游原料
共找到12个上游原料 >