(2S)-2-((4-(((2,7-二甲基-4-氧代-1,4-二氢喹唑啉-6-基)甲基)(丙-2-炔基)氨基)-2-氟苯甲酰)氨基)-4-(1H-四唑-5-基)丁酸

(2S)-2-((4-(((2,7-二甲基-4-氧代-1,4-二氢喹唑啉-6-基)甲基)(丙-2-炔基)氨基)-2-氟苯甲酰)氨基)-4-(1H-四唑-5-基)丁酸

CAS号：865466-24-6

英文名：(1R,2S,5S)-3-[(2S)-2-[[1-(tert-butylsulfonylmethyl)cyclohexyl]carbamoylamino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

分子式

C36H61N5O7S

熔点

密度

1.21

分子量

707.964

沸点

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

基本信息

中文名称

(2S)-2-((4-(((2,7-二甲基-4-氧代-1,4-二氢喹唑啉-6-基)甲基)(丙-2-炔基)氨基)-2-氟苯甲酰)氨基)-4-(1H-四唑-5-基)丁酸

英文名称

(1R,2S,5S)-3-[(2S)-2-[[1-(tert-butylsulfonylmethyl)cyclohexyl]carbamoylamino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

中文别名

英文别名

narlaprevir、CS-0445、(1R,5S)-N-[1(S)-[2-(cyclopropylamino)-1,2-dioxoethyl]pentyl]-3-[2(S)-[[[[1-[[(1,1-dimethylethyl)sulfonyl]methyl]cyclohexyl]amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2(S)-carboxamide、(1R,2S,5S)-3-((S)-2-(3-(1-(tert-butylsulfonylmethyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-N-((S)-1-(cyclopropylamino)-1,2-dioxoheptan-3-yl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide、Narlaprevir (USAN/INN)

CAS号

865466-24-6

分子式

C36H61N5O7S

分子量

707.964

精确质量

707.429

PSA

186.21

LOGP

6.4674

编号系统

UNII

2857LA2O07

物化性质

密度

1.21

合成路线

(1R,2S,5S)-3-((S)-2-(3-(1-((tert-butylsulfonyl)methyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-N-((2S,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxoheptan-3-yl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-3-((S)-2-(3-(1-((tert-butylsulfonyl)methyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-N-((2S,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxoheptan-3-yl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(2S)-2-((4-(((2,7-二甲基-4-氧代-1,4-二氢喹唑啉-6-基)甲基)(丙-2-炔基)氨基)-2-氟苯甲酰)氨基)-4-(1H-四唑-5-基)丁酸

(2S)-2-((4-(((2,7-二甲基-4-氧代-1,4-二氢喹唑啉-6-基)甲基)(丙-2-炔基)氨基)-2-氟苯甲酰)氨基)-4-(1H-四唑-5-基)丁酸

上游原料

共找到21个上游原料 >

叔丁基硫化甲烷

叔丁基硫化甲烷

3-Methyl-N-[(1-{[(2-methyl-2-propanyl)sulfonyl]methyl}cyclohexyl) carbamoyl]-L-valine

3-Methyl-N-[(1-{[(2-methyl-2-propanyl)sulfonyl]methyl}cyclohexyl) carbamoyl]-L-valine

N-(1-((tert-butylsulfonyl)methyl)cyclohexyl)-2-methylpropane-2-sulfinamide

N-(1-((tert-butylsulfonyl)methyl)cyclohexyl)-2-methylpropane-2-sulfinamide

2-庚烯酸

1-((tert-butylsulfonyl)methyl)cyclohexane-1-carboxylic acid

1-((tert-butylsulfonyl)methyl)cyclohexane-1-carboxylic acid

(2S,3S)-tert-butyl 3-(benzyl((S)-1-phenylethyl)amino)-2-hydroxyheptanoate

(2S,3S)-tert-butyl 3-(benzyl((S)-1-phenylethyl)amino)-2-hydroxyheptanoate

上游原料

叔丁基硫化甲烷 3-Methyl-N-[(1-{[(2-methyl-2-propanyl)sulfonyl]methyl}cyclohexyl) carbamoyl]-L-valine N-(1-((tert-butylsulfonyl)methyl)cyclohexyl)-2-methylpropane-2-sulfinamide 2-庚烯酸 1-((tert-butylsulfonyl)methyl)cyclohexane-1-carboxylic acid (2S,3S)-tert-butyl 3-(benzyl((S)-1-phenylethyl)amino)-2-hydroxyheptanoate N-cyclohexylidene-2-methylpropane-2-sulfinamide 1-((tert-butylsulfonyl)methyl)-1-isocyanatocyclohexane phenyl (1-((tert-butylsulfonyl)methyl)cyclohexyl)carbamate (2S,3S)-3-(benzyl((S)-1-phenylethyl)amino)-N-cyclopropyl-2-hydroxyheptanamide 环己甲酸甲酯 (1R,2S,5S)-6,6-Dimethyl-3-{3-methyl-N-[(1-{[(2-methyl-2-propanyl) sulfonyl]methyl}cyclohexyl)carbamoyl]-L-valyl}-3-azabicyclo[3.1.0 ]hexane-2-carboxylic acid 2-甲基-2-甲基磺酰基-丙烷 (1R,2S,5S)-3-[(2S)-2-[[1-(tert-butylsulfonylmethyl)cyclohexyl]carbamoylamino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-2-hydroxy-1-oxoheptan-3-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyheptanamide hydrochloride 1-甲氧基-1-三甲基甲硅烷基氧基亚甲基环己烷戊醛 (1R,2S,5S)-3-((S)-2-(3-(1-((tert-butylsulfonyl)methyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-N-((2S,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxoheptan-3-yl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide 环己酮 (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyheptanamide (2S,3S)-3-(benzyl((S)-1-phenylethyl)amino)-2-hydroxyheptanoic acid