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9-甲氧基喜树碱
CAS号:19685-10-0
英文名:9-methoxycamptothecine
分子式:C21H18N2O5
分子量:378.378
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合成路线
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(4S)-4-ethyl-3,4-dihydroxy-9-methoxy-3,4-dihydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-14(12H)-one
19685-10-0
9-甲氧基喜树碱
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4-甲氧基苯异腈
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(S)-4-Ethyl-4-hydroxy-6-iodo-3-oxo-7-propargyl-1H-pyrano[3,4-c]-8-pyridone
19685-10-0
9-甲氧基喜树碱
186581-53-3
重氮甲烷
19685-09-7
羟基喜树碱
19685-10-0
9-甲氧基喜树碱
19685-09-7
羟基喜树碱
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甲基碘
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9-甲氧基喜树碱
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喜树碱
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9-甲氧基喜树碱
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4-ethyl-4-hydroxy-1,5b,6,11,11a,12-hexahydro-4H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
19685-10-0
9-甲氧基喜树碱
161681-84-1
1-benzyl 3-methyl 2-(2,2-dimethoxyethylidene)malonate
19685-10-0
9-甲氧基喜树碱
173442-34-7
(S)-4-ethyl-4-hydroxy-6-iodo-3-oxo-1H-pyrano[3,4-c]-8-pyridone
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9-甲氧基喜树碱
174092-79-6
(S)-4-ethyl-4-hydroxy-6-iodo-8-methoxy-1,4-dihydro-pyrano[3,4-c]pyridin-3-one
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9-甲氧基喜树碱
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9-硝基喜树碱
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9-甲氧基喜树碱
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上游原料
重氮甲烷
4-iodo-2-methoxy-6-trimethylsilanyl-3-pyridinecarboxaldehyde
10-氨基喜树碱
1-benzyl 3-methyl 2-(2,2-dimethoxyethylidene)malonate
(S)-4-ethyl-4-hydroxy-6-iodo-3-oxo-1H-pyrano[3,4-c]-8-pyridone
9-硝基喜树碱
(S)-4-ethyl-4-hydroxy-6-iodo-8-methoxy-1,4-dihydro-pyrano[3,4-c]pyridin-3-one
喜树碱氮氧化物
(S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-(3-(hydroxymethyl)-2-methoxypyridin-4-yl)propan-1-ol
2-甲氧基-6-(三甲基硅烷基)吡啶
4-ethyl-8-methoxy-6-(trimethylsilyl)-1H-pyrano[3,4-c]pyridine
4-((S)-1-(benzyloxy)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-propyl)-3-((benzyloxy)methyl)-2-methoxypyridine
(S)-(+)-4-ethyl-4-hydroxy-8-methoxy-6-(trimethylsilyl)-1,4-dihydro-3H-pyrano[3,4-c]pyridin-3-one
甲基碘
喜树碱
(S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-ethyl-4-methoxyfuro[3,4-c]pyridin-3(1H)-one
2-methoxy-6-(trimethylsilyl)nicotinaldehyde
(S)-4-ethyl-4-hydroxy-8-methoxy-1H-pyrano[3,4-c]pyridin-3(4H)-one
2-甲氧基烟酸
羟基喜树碱
4-ethyl-4-hydroxy-1,5b,6,11,11a,12-hexahydro-4H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
methyl 7-methoxy-1,3-dihydro-2H-pyrrolo[3,4-b]quinoline-2-carboxylate
(S)-4-Ethyl-4-hydroxy-6-iodo-3-oxo-7-propargyl-1H-pyrano[3,4-c]-8-pyridone
(S)-2-(benzyloxy)-2-(3-((benzyloxy)methyl)-2-methoxypyridin-4-yl)butanoic acid
(4R,5bS,11aS)-4-ethyl-4-hydroxy-9-nitro-1,5b,6,11,11a,12-hexahydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
(S)-2-(benzyloxy)-2-(3-((benzyloxy)methyl)-2-methoxypyridin-4-yl)butanal
(4S)-4-乙基-4-羟基-1H-吡喃并[3,4-c]吡啶-3,8(4h,7h)-二酮
(+/-)-4-ethyl-4-hydroxy-8-methoxy-6-(trimethylsilyl)-1,4-dihydro-3H-pyrano[3,4-c]pyridin-3-one
methyl 7-((2R,4S)-2-(tert-butyl)-4-ethyl-5-oxo-1,3-dioxolan-4-yl)-2-methoxy-9-oxo-9,11-dihydroindolizino[1,2-b]quinoline-8-carboxylate
(4S)-4-ethyl-3,4-dihydroxy-9-methoxy-3,4-dihydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-14(12H)-one
甲醇
(2R,3S)-3-(benzyloxy)-3-(3-((benzyloxy)methyl)-2-methoxypyridin-4-yl)pentane-1,2-diol
4-甲氧基苯异腈
下游产品
(4S)-4alpha-乙基-4-羟基-7-氨基-1H-吡喃并[3',4':6,7]吲哚嗪并[1,2-b]喹啉-3,14(4H,12H)-二酮
拓普替康
羟基喜树碱