商品
首页
百科
拉坦前列素

拉坦前列素

CAS号：130209-82-4
英文名：latanoprost
分子式
C26H40O5
熔点
密度
1.093 g/cm3
分子量
432.593
沸点
583.8ºC at 760 mmHg
溶解度
信号词
危险品标志
若想填写更详细的询价信息，请点击进入询价页面
点我
化合物简介
Latanoprost eye solution is a medication administered into the eyes to control the progression of glaucoma or ocular hypertension by reducing intraocular pressure (IOP). It is a prostaglandin analogue (more specifically an analogue of prostaglandin F2α) that lowers the pressure by increasing the outflow of aqueous fluid from the eyes through the uveoscleral tract. Latanoprost is an isopropyl ester prodrug, meaning it is inactive until it is hydrolyzed by esterases in the cornea to the biologically active acid.
基本信息
中文名称
拉坦前列素
英文名称
latanoprost
中文别名
拉坦前列腺素、7-[3,5-二羟基-2-(3-羟基-5-苯基戊基)-环戊烷]庚-5-烯酸异丙酯、[1R-[1Α(Z),2Β(R^^),3Α,5Α]]-7-[3,5-二羟基-2-(3-羟基-5-苯基戊基)环戊基]-5-庚烯酸1-甲基乙基酯
英文别名
XALATAN、xa41、Latanoprost、Xalata、phxa41、LATANAPROST、Lata prostaglandin
CAS号
130209-82-4
分子式
C26H40O5
分子量
432.593
精确质量
432.288
PSA
86.99
LOGP
4.1864
编号系统
UNII
6Z5B6HVF6O
物化性质
外观与性状
淡黄色油状
密度
1.093 g/cm3
沸点
583.8ºC at 760 mmHg
闪点
188.3ºC
折射率
1.537
储存条件
-20ºC
安全信息
RTECS号
MJ9669550
WGK Germany
3
海关编码
2937500000
生产方法及用途
生产方法
以3.3a,4,5,6,6a-六氢-2-氧-4-羟甲基-5-(4-苯基苯甲酰氧基)-2H-环戊烷并[b]为起始原料,经几步反应得到。
用途
用于治疗青光眼和高眼压症，以及其他各种眼压升高的情况。
合成路线
共找到1条合成路线 >
2-碘代丙烷
75-30-9
2-碘代丙烷
拉坦前列腺素(游离酸)
41639-83-2
拉坦前列腺素(游离酸)
拉坦前列素
130209-82-4
拉坦前列素
上游原料
共找到46个上游原料 >
2-溴丙烷
75-26-3
2-溴丙烷
(3aR,4R,5R,6aS)-5-(tert-butyldimethylsilyloxy)-4-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-ol
1240483-22-0
(3aR,4R,5R,6aS)-5-(tert-butyldimethylsilyloxy)-4-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-ol
(R)-2-allyl-4-(tert-butyldimethylsilyloxy)cyclopent-2-enone
98974-31-3
(R)-2-allyl-4-(tert-butyldimethylsilyloxy)cyclopent-2-enone
(Z)-7-((1R,2R,3R,5S)-5-hydroxy-3-((2-methoxyethoxy)methoxy)-2-((R)-3-((2-methoxyethoxy)methoxy)-5-phenylpentyl)cyclopentyl)hept-5-enoic acid
1300092-85-6
(Z)-7-((1R,2R,3R,5S)-5-hydroxy-3-((2-methoxyethoxy)methoxy)-2-((R)-3-((2-methoxyethoxy)methoxy)-5-phenylpentyl)cyclopentyl)hept-5-enoic acid
(1S,2R,3R,4R)-2-allyl-4-((tert-butyldimethylsilyl)oxy)-3-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)cyclopentyl hex-5-enoate
1261926-69-5
(1S,2R,3R,4R)-2-allyl-4-((tert-butyldimethylsilyl)oxy)-3-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)cyclopentyl hex-5-enoate
(3aR,4R,5R,6aS)-5-(tert-butyldiphenylsilyloxy)-4-((E)-3-oxo-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-one
1395619-06-3
(3aR,4R,5R,6aS)-5-(tert-butyldiphenylsilyloxy)-4-((E)-3-oxo-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-one
下游产品
共找到1个下游商品 >
拉坦前列腺素(游离酸)
41639-83-2
拉坦前列腺素(游离酸)
上游原料
2-溴丙烷 (3aR,4R,5R,6aS)-5-(tert-butyldimethylsilyloxy)-4-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-ol (R)-2-allyl-4-(tert-butyldimethylsilyloxy)cyclopent-2-enone (Z)-7-((1R,2R,3R,5S)-5-hydroxy-3-((2-methoxyethoxy)methoxy)-2-((R)-3-((2-methoxyethoxy)methoxy)-5-phenylpentyl)cyclopentyl)hept-5-enoic acid (1S,2R,3R,4R)-2-allyl-4-((tert-butyldimethylsilyl)oxy)-3-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)cyclopentyl hex-5-enoate (3aR,4R,5R,6aS)-5-(tert-butyldiphenylsilyloxy)-4-((E)-3-oxo-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-one (1S,2R,3R,4R)-2-allyl-4-((tert-butyldimethylsilyl)oxy)-3-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)cyclopentan-1-ol (3aR,4R,5R,6aS)-5-((2-methoxyethoxy)methoxy)-4-((R)-3-((2-methoxyethoxy)methoxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-ol (1S,5R,6R,7R)-6-[(3S)-3-hydroxy-5-phenyl-1-pentenyl]-7-[(4-phenylbenzoyl)oxy]-2-oxabicyclo[3.3.0]octan-3-one (2R,3R,4R)-2-allyl-4-((tert-butyldimethylsilyl)oxy)-3-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)cyclopentan-1-one isopropyl (Z)-7-((1R,2R,3R,5S)-5-hydroxy-2-((R)-5-phenyl-3-((triethylsilyl)oxy)pentyl)-3-((triethylsilyl)oxy)cyclopentyl)hept-5-enoate sodium 5-(triphenyl-l<sup>5</sup>-phosphanylidene)pentanoate (3aR,4R,5R,6aS)-5-((2-methoxyethoxy)methoxy)-4-((R)-3-((2-methoxyethoxy)methoxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one latanoprost L-arginine salt 对苯基苯甲酰Corey醛 isopropyl (Z)-7-((1R,2R,3R,5S)-2-((3R)-5-phenyl-3-((tetrahydro-2H-pyran-2-yl)oxy)pentyl)-3,5-bis((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)hept-5-enoate (3aR,4S,5R,6aS)-5-(tert-butyldiphenylsilyloxy)-4-(trityloxymethyl)hexahydro-2H-cyclopenta [b] furan-2-one 异丙醇 (3aR,4S,5R,6aS)-(-)-六氢-4-(羟甲基)-2-氧代-2H-环戊并[b]呋喃-5-基 1,1'-联苯-4-甲酸酯 拉坦前列腺素(游离酸) 4-羧丁基三苯基溴化膦 isopropyl (Z)-7-((1R,2R,3R)-3-hydroxy-2-((R)-3-hydroxy-5-phenylpentyl)-5-oxocyclopentyl)hept-5-enoate 拉坦前列素中间体 溴化苄 (Z)-isopropyl 7-((1R,2R,3R,5S)-5-hydroxy-3-((2-methoxyethoxy)methoxy)-2-((R)-3-((2-methoxyethoxy)methoxy)-5-phenylpentyl)cyclopentyl)hept-5-enoate (3aR,4R,5R,6aS)-5-((tert-butyldimethylsilyl)oxy)-4-((E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one (1S,5R,6R,7R)-6-[(3R)-3-hydroxy-5-phenyl-1-pentyl]-7(R)-hydroxy-2-oxabicyclo[3.3.0]octan-3-one 2-碘代丙烷 5-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-2-氧代六氢-2H-环戊二烯并[b]呋喃-4-甲醛 (3aR,4R,5R,6aS)-5-(tert-butyldiphenylsilyloxy)-4-((S,E)-3-hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-ol (-)-7α-hydroxy-6β-triphenylmethoxymethyl-cis-2-oxabicyclo[3.3.0]octan-3-one (3aR,4R,5R,6aS)-5-(tert-butyldiphenylsilyloxy)-4-((S,E)-3-hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-one (-)-6beta-羟甲基-7alpha-羟基-顺式-2-氧杂双环[3.3.0]辛-3-酮 tert-butyl[(1S)-3-iodo-1-phenethylpropyl]oxydimethylsilane (3aR,4R,5R,6aS)-六氢-2-氧代-4-[(1E)-3-氧代-5-苯基-1-戊烯基]-2H-环戊并[b]呋喃-5-基 [1,1’-联苯]-4-甲酸酯 拉坦前列腺素内半缩醛 拉坦前列腺素 (3aR,4R,5R,6aS)-5-(tert-butyldimethylsilyloxy)-4-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one 2-氧代-4-苯丁基磷酸二甲酯 (3aR,4R,5R,6aS)-5-((tert-butyldimethylsilyl)oxy)-4-((R)-3-hydroxy-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one (3aR,4S,5R,6aS)-4-((tert-butyldimethylsilyloxy)methyl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one (Z)-7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)-5-hydroxycyclopentyl)hept-5-enoic acid
下游产品
拉坦前列腺素(游离酸)
按化学品名称查询∶
ABCDEFGHIJKLMNOPQRSTUVWXYZ0123456789
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床判断或治疗，非药用，非食用。

增值电信业务许可证 举报电话: 400-612-5272

Copyright © Shanghai Milkyway Supply Chain Management Co., Ltd. 上海密尔克卫供应链管理有限公司 | 工商 经营证照 沪ICP备2024054240号-1