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(-)-6beta-羟甲基-7alpha-羟基-顺式-2-氧杂双环[3.3.0]辛-3-酮

(-)-6beta-羟甲基-7alpha-羟基-顺式-2-氧杂双环[3.3.0]辛-3-酮

CAS号:32233-40-2
英文名:(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one
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化合物简介
(-)-Corey Lactone Diol is an intermediate of Iloprost and shows inhibitory activity towards β-lactamase. Iloprost is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
基本信息
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物化性质
安全信息
上游原料
(3AR,4S,5R,6AS)-4-[(乙酰氧基)甲基]六氢-5-羟基-2H-环戊并[B]呋喃-2-酮 2-{(1R,6S)-6-[(1E)-1,3-butadienyl]-3,3-dimethyl-2,4-dioxacyclohexyl}ethanol (1R,4S)-顺-4-乙酰氧基-2-环戊烯-1-醇 (1S,2S,6R,8S)-10,10-dimethyl-5,9,11-trioxatricyclo[6.4.0.02,6]dodecan-4-one (-)-trans-2-carboxymethylcyclopent-3-en-1-ol 2-methoxycarbonylmethyl-4-hydroxy-2-cyclopenten-1-one (1SR, 5RS, 6RS, 7RS)-7-acetoxy-6-acetoxymethyl-2-oxabicyclo<3.3.0>octan-3-one (3aR,4S,5R,6aS)-(-)-六氢-4-(羟甲基)-2-氧代-2H-环戊并[b]呋喃-5-基 1,1'-联苯-4-甲酸酯 6-噁双环[3.1.0]-3-己烯 (4R)-(+)-羟基-2-环戊酮 (4R,5S)-4-(2-tert-butyldimethylsilyloxyethyl)-2,2-dimethyl-1,3-dioxa-5-ethenylcyclohexane 乙酸酐 3,4-二氢-2H-吡喃 (4aS,4bR,7aS,8aR)-hexahydrofuro[3',2':3,4]cyclopenta[1,2-d][1,3]dioxin-6(7aH)-one <3aR(3aα,4α,5β,6aα)>-(-)-<5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-2H-cyclopenta<b>furan-2-on-4-yl>methyl hydrogen pentanedioate (3aR,4S,5R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate methyl 2-(5-oxocyclopenten-1-yl)acetate <3aR(3aα,4α,5β,6aα)>-(-)-<5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-2H-cyclopenta<b>furan-2-on-4-yl>methyl hydrogen butanedioate methyl 2R-methylsulfonyloxy-4-cyclopentene-1R-acetate 甲醛 ((3aR,4S,6aS)-5-乙酰氧基-2-氧代六氢-2H-环戊并[b]呋喃-4-基)甲基 乙酸酯 (-)-trans-2-methoxycarbonylmethylcyclopent-3-en-1-ol [(R)-5-Oxo-3-(tetrahydro-pyran-2-yloxy)-cyclopent-1-enyl]-acetic acid methyl ester (3aR,4S,5R,6aS)-4-((tert-butyldimethylsilyloxy)methyl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one (3S,1'R)-5-(1'-carboxy-3'-methylbutoxy)imino-3-hydroxy-1-cyclopentene-1-acetic acid methyl ester (2E)-3-[(1S,2R)-2-(2-tert-butyldimethylsilyloxyethyl)-4,4-dimethyl-3,5-dioxacyclohexyl]-2-propen-1-ol trans-2-cyanomethylcyclopent-3-en-1-ol (3aR,4S,5R,6aS)-5-{[(tert-butyl)(dimethyl)silyl]oxy}-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]furan-2-one (2R,3S)-5-tert-butyldimethylsilyloxy-2,3-epoxypentan-1-ol 顺式-4-环戊烯-1,3-二醇 科立内酯 [(3aR,4S,5R,6aS)-4-(hydroxymethyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] acetate 前列腺素中间体 科里内酯 methyl 2-((1S,2R,3S)-2-(nitromethyl)-5-oxo-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)acetate 2-oxa-3-oxo-6-syn-acetoxymethyl-7-anti-hydroxy-cis-bicyclo[3,3,0]octane methyl (2E)-2-[(1S,2R)-tert-butyldimethylsilyloxyethyl-4,4-dimethyl-3,5-dioxacyclohexyl]2-propenoate (1S,2S,6R,8S)-10,10-dimethyl-5,9,11-trioxatricyclo[6.4.0.02,6]dodecan-4-ol (2S,3R)-5-tert-butyldimethylsilyloxy-2-ethenylpentan-1,3-diol (3aR,4R,5R,6aS)-hexahydro-2-oxo-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-cyclopenta[b]furan-4-carboxaldehyde 5-(tert-butyldimethylsilyloxy)pent-2-en-1-ol methyl 2-[(3R)-3-hydroxy-5-oxocyclopenten-1-yl]acetate 糠醇 (3aα,4α,5β,6aα)-hexahydro-4-nitromethyl-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-cyclopenta[b]furan-2-one (1R,6S,7R,8S)-3,3-dimethyl-2,4-dioxa-7-(2-propenyl)bicyclo[4.3.0]nonan-8-ol (3aR,4S,5R,6aS)-4-[[[(1,1-二甲基乙基)二甲基硅基]氧基]甲基]六氢-5-[(四氢-2H-吡喃-2-基)氧基]-2H-环戊并[b]呋喃-2-酮