化合物简介
Fumaric acid monomethyl ester is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. Fumaric acid monomethyl ester is potent nicotinic acid receptor agonist. Fumaric acid monomethyl ester has also been shown to selectively stimulate of T helper 2 cytokine response. It is also the active metabolite of Dimethyl Fumarate, a compound that is used as a treatment for the relapsing forms of multiple sclerosis and psoriasis.
基本信息
中文名称
富马酸单甲酯
英文名称
Fumaric Acid Monomethyl Ester
中文别名
英文别名
Monomethyl Fumarate、4-Methoxy-4-oxobut-2-enoic acid、Methyl Hydrogen Fumarate、Monomethyl fumarate
CAS号
2756-87-8
分子式
C5H6O4
分子量
130.099
精确质量
130.027
PSA
63.6
LOGP
-0.1998
编号系统
MDL号
MFCD00063174
物化性质
密度
1.265 g/cm3
沸点
250ºC at 760mmHg
熔点
144-145ºC
闪点
108.9ºC
折射率
1.468
蒸汽压
0.00706mmHg at 25°C
安全信息
安全说明
S26-S39
WGK Germany
3
危险类别码
R41
海关编码
2918990090
危险品标志
Xi
生产方法及用途
用途
用作饲料防霉剂
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