百科

5-羟甲基脱氧尿苷

CAS号：5116-24-5

英文名：5-hydroxymethyl-2'-deoxyuridine

分子式

C10H14N2O6

熔点

密度

1.561g/cm3

分子量

258.228

沸点

溶解度

信号词

危险品标志

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化合物简介

5-Hydroxymethyl-2’-deoxyuridine acts as a biomarker for the diagnosis for oxidative stress in humans. Used as a diagnostic to for propensitiy for the development of breast cancer.

基本信息

中文名称

5-羟甲基脱氧尿苷

英文名称

5-hydroxymethyl-2'-deoxyuridine

中文别名

2\'-脱氧-5-羟甲基尿甙、5-羟基甲基-2-脱氧尿苷、5-羟甲基尿嘧啶脱氧核苷

英文别名

5-HMdU HMdUdr、5-HYDROXYMETHYL-2\'-DEOXYURIDINE

CAS号

5116-24-5

分子式

C10H14N2O6

分子量

258.228

精确质量

258.085

PSA

124.78

LOGP

-2.3304

编号系统

MDL号

MFCD00047489

物化性质

密度

1.561g/cm3

折射率

1.61

储存条件

-20ºC

安全信息

海关编码

2934999090

合成路线

上游原料

1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-((phenylthio)methyl)pyrimidine-2,4(1H,3H)-dione

6979-97-1

3,5-双-O-乙酰胸苷

40733-26-4

3,5-双-o-(t-丁基二甲基甲硅烷基)胸腺嘧啶脱氧核苷

354581-59-2

3',5'-bis(O-tert-butyldimethylsilyl)-5-hydroxymethyl-2'-deoxyuridine

6974-32-9

1-乙酰基-2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖

下游产品

5-(azidomethyl)-5'-azido-2',5'-dideoxyuridine

19140-39-7

(5S)-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-diazinane-2,4-dione

50-89-5

胸苷

上游原料

2'-脱氧尿苷 1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-((phenylthio)methyl)pyrimidine-2,4(1H,3H)-dione 3,5-双-O-乙酰胸苷 3,5-双-o-(t-丁基二甲基甲硅烷基)胸腺嘧啶脱氧核苷 3',5'-bis(O-tert-butyldimethylsilyl)-5-hydroxymethyl-2'-deoxyuridine 1-乙酰基-2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖 5-(2-nitro-1H-imidazol-1-ylmethyl)-2'-deoxythymidine 3',5'-bis-O-(acetyl)-5-methylselenylmethyl-2'-deoxyuridine 3',5'-bis-O-(tert-butyldiphenylsilyl)-5-phenylselenylmethyl-2'-deoxyuridine (5-bromomethyl)-3',5'-di-O-acetyl-2'-deoxyuridine 5-(N-methoxymethylamine)-2'-deoxyuridine 胸苷溴代醇 6-hydroxy-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylidene-1,3-diazinane-2,4-dione 5-methylselenyl-methyl-2'-deoxy uridine (5R,6R)-5-bromo-6-hydroxy-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-diazinane-2,4-dione 5-甲基-2'-脱氧胞苷 5-(phenylthiomethyl)-2'-deoxyuridine 2'-脱氧-5-(羟甲基)胞啶 3',5'-bis-O-acetyl-5-(4-nitro-1H-imidazol-1-ylmethyl)-2'-deoxythymidine 3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine 1-((2R,4S,5R)-4-羟基-5-(羟基甲基)四氢呋喃-2-基)-2,4-二氧代-1,2,3,4-四氢嘧啶-5-甲醛 1-((5S,6S)-6-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2,4-dioxohexahydropyrimidin-5-yl)-2,2,6,6-tetramethyl-4-oxopiperidine 1-oxide 3',5'-bis-O-(tert-butyldiphenylsilyl)-5-bromomethyl-2'-deoxyuridine 5-羟甲基尿嘧啶 (5RS,6RS)-5-bromo-6-hydroxy-5,6-dihydrothymidine 甲醛胸苷尿嘧啶核苷 3',5'-bis-O-(tert-butyldimethylsilyl)-5-(bromomethyl)-2'-deoxyuridine

下游产品

2'-脱氧-5-(羟甲基)胞啶 5-叠氮基甲基-2'-脱氧尿苷 5-(azidomethyl)-5'-azido-2',5'-dideoxyuridine (5S)-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-diazinane-2,4-dione 胸苷