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![(3aR,4R,9R,9aR)-4,6,7-trihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one](https://cdn-oss.0elem.com/prod/mob/images/138/138456-90-3.jpg)
![(3aR,4S,9R,9aR)-4,6,7-trihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one](https://cdn-oss.0elem.com/prod/mob/images/138/138456-91-4.jpg)
![(5S,5aR,8aR,9R)-5-ethylsulfanyl-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one](https://cdn-oss.0elem.com/prod/mob/images/118/118356-06-2.jpg)
![5-chloro-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one](https://cdn-oss.0elem.com/prod/mob/images/740/7401-22-1.jpg)
![5,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮](https://cdn-oss.0elem.com/prod/mob/images/437/4375-07-9.jpg)
![(5R)-5-(3,4,5-trimethoxyphenyl)-8,9-dihydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one](https://cdn-oss.0elem.com/prod/mob/images/477/477-52-1.jpg)
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鬼臼毒素
CAS号：518-28-5
英文名：podophyllotoxin
分子式：C22H22O8
分子量：414.405
上游原料
5,6-dihydrocyclobuta[4,5]benzo[1,2-d][1,3]dioxol-5-ol
鬼臼毒素-4-O-葡萄糖苷
4-(dimethoxy)methyl-5-formyl(1,2-methylenedioxy)benzene
3,4-二甲氧基苯乙酮
2''-bromophenyl (3R,4R)-6,7-methylenedioxy-3-triisopropylsilyloxymethyl-4-(2'-trimethylsilylethoxy)methoxy-3,4-dihydronaphthalene-2-carboxylate
(1R,2S,3R,4R)-4-O-(2-trimethylsilylethoxy)methylpicropodophyllin
丙酮
(1S,2S,3R,4R)-2-acetoxymethyl-1,4-epoxy-6,7-methylenedioxy-3-triisopropylsilyloxymethyl-1,2,3,4-tetrahydronaphthalene
(-)-3-(hydroxymethyl)picropodophyllone
(3R,4R)-2-formyl-4-hydroxy-6,7-methylenedioxy-3-triisopropylsilyloxymethyl-3,4-dihydronaphthalene
5,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮
环丁酮
(3R,4R)-6,7-methylenedioxy-3-triisopropylsilyloxymethyl-4-(2'-trimethylsilylethoxy)methoxy-3,4-dihydronaphthalene-2-carboxylic acid
苦鬼臼毒素
meso-(1R*,2R*,3S*,4S*)-2,3-bis(acetoxymethyl)-1,4-epoxy-6,7-methylenedioxy-1,2,3,4-tetrahydronaphthalene
5-bromo-6-(dimethoxymethyl)-1,3-benzodioxole
4’-去甲鬼臼毒素
2-[6-(3,4,5-trimethoxybenzoyl)-1,3-benzodioxol-5-yl]acetic acid
(5R,5aR,8R,8aR,9R)-8-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,5a,8a,9-tetrahydro-5,9-(epoxymethano)furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole-6,11(8H)-dione
dimethyl meso-(1R*,2S*,3R*,4S*)-(endo)-1,4-epoxy-6,7-methylenedioxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboxylate
(5R,5aS,6R,8aR,9R)-6-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-8-oxo-9-(3,4,5-trimethoxy-phenyl)-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole-5-carboxylic acid
6-溴-3,4-亚甲基二氧苯甲醛
(-)-Methyl epipodophyllate
(5R)-5-(3,4,5-trimethoxyphenyl)-8,9-dihydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one
重氮甲烷
(-)-4-O-(tert-butyldimethylsilyl)podophyllotoxin
3,4,5-三甲氧基苯甲醛
(-)-(1R,2S,3S)-1-(3,4,5-trimethoxyphenyl)-2-(methoxycarbonyl)-3-<<(tert-butyldimethylsilyl)oxy>methyl>-6,7-(methylenedioxy)-2,3-dihydro-4(1H)-naphtalenone
α-apopicropodophyllic acid
盐酸
(5R,6R,7R,8R)-methyl 8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylate
(+)-4-O-(tert-butyldimethylsilyl)picropodophyllin
(3R,4R)-6,7-methylenedioxy-2-(N-oxazolidinoyl)carbonyl-3-triisopropylsilyloxymethyl-4-(2'-trimethylsilylethoxy)methoxy-3,4-dihydronaphthalene
(1R,2S,3R,4R)-6,7-methylenedioxy-2-(N-oxazolidinoyl)carbonyl-3-triisopropylsilyloxymethyl-1-(3',4',5'-trimethoxy)phenyl-4-(2''-trimethylsilylethoxy)methoxy-1,2,3,4-tetrahydronaphthalene
(-)-(1R,2S)-1-(3,4,5-trimethoxyphenyl)-2-(methoxycarbonyl)-3-(((tert-butyldimethylsilyl)oxy)methyl)-6,7-(methylenedioxy)-1,2-dihydronaphtalene
[(5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl] acetate
(1S,2S,3R,4R)-1,4-epoxy-2-hydroxymethyl-6,7-methylenedioxy-3-triisopropylsilyloxymethyl-1,2,3,4-tetrahydronaphthalene
dimethyl 1,4-dihydro-1,4-epoxy-6,7-methylenedioxy-2,3-naphthalene-dicarboxylate
(5R)-5,8,8ab,9-四氢-5b-(3,4,5-三甲氧基苯基)呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5abH),9-二酮
(1R,2R,3R,4R)-4-O-(2'-trimethylsilylethoxy)methylpodophyllotoxin
6,7-methylenedioxy-1-(3',4',5'-trimethoxyphenyl)-2-benzopyran-3-one
(5S,5aS,6R,8aR,9R)-6-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl acetate
4-(dimethoxy)methyl-5-hydroxymethyl(1,2-methylenedioxy)benzene
(5R,5aR,6R)-6-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxole-5-carboxylic acid
meso-(1R*,2R*,3S*,4S*)-2,3-bis(hydroxymethyl)-1,4-epoxy-6,7-methylenedioxy-1,2,3,4-tetrahydronaphthalene
5-chloro-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
下游产品
鬼臼毒素-4-O-葡萄糖苷
苦鬼臼毒素
4'-demethyl-β-apopicropodophyllotoxin
6-(3,4,5-trimethoxybenzoyl)-1,3-benzodioxole-5-carboxylic acid
4'-demethyl-1-O-ethyl-1-epipodophyllotoxin
picropodophyllotoxin ethyl ether
(3aR,4R,9R,9aR)-4,6,7-trihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one
4’-去甲鬼臼毒素
(3aR,4S,9R,9aR)-4,6,7-trihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one
6,7-O,O-demethylenepodophyllotoxin
epipicropodophyllotoxin ethyl ether
4 ’-去甲去氧鬼臼毒素
(5S,5aR,8aR,9R)-5-ethylsulfanyl-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
5-chloro-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
5,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮
3',4'-didemethylepipodophyllotoxin
3',4',5'-tridemethylepipodophyllotoxin
(5R)-5-(3,4,5-trimethoxyphenyl)-8,9-dihydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one
podophyllotoxin
3,4,5-三甲氧基苯甲酸
(5S,5aS,8aR,9R)-5-[(4-氟苯基)氨基]-9-(4-羟基-3,5-二甲氧基-苯基)-5a,6,8a,9-四氢-5H-异苯并呋喃并[5,6-f][1,3]苯并二氧戊环-8-酮
4'-去甲氧基表鬼臼毒素
(3aS,4S,9R,9aR)-4-(4-fluoroanilino)-6,7-dihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-3a,4,9,9a-tetrahydro-3H-benzo[f][2]benzofuran-1-one
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