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β-烟酰胺腺嘌呤二核苷酸

β-烟酰胺腺嘌呤二核苷酸

CAS号:53-84-9
英文名:β-Nicotinamide adenine dinucleotide
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化合物简介
β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
基本信息
编号系统
物化性质
安全信息
生产方法及用途
生产方法
酵母经沸水提取,醋酸铅酸化沉淀得粗品,经甲酸型阳离子交换树脂柱处理,精制而得。
用途
参与体内的能量代谢和物质代谢,有利于细胞的修复和更新。用于冠心病、心肌炎、白细胞减少等症的治疗。