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2'-脱氧尿苷

2'-脱氧尿苷

CAS号：951-78-0

英文名：2'-deoxyuridine

分子式

C9H12N2O5

熔点

167-169°C(lit.)

密度

1.533 g/cm3

分子量

228.202

沸点

溶解度

300 g/L (20 ºC)

信号词

危险品标志

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化合物简介

Deoxyuridine (dU) is a compound and a nucleoside. It is similar in chemical structure to uridine, but without the 2'-hydroxyl group.

基本信息

中文名称

2'-脱氧尿苷

英文名称

2'-deoxyuridine

中文别名

2’-脱氧尿嘧啶核苷、2’-脱氧尿苷、2\'-脱氧尿嘧啶核苷、1-(2-Deoxy-β-D-ribofuranosyl)uracil、2\'-去氧尿苷、2\'-脱氧尿甙、去氧尿嘧啶核苷

英文别名

[131I]-Deoxyuridine、DEOXYURIDINE-2\'、2\'-deoxy-uridin、2\'-Deoxyuridine、deoxyuridine、Uracildeoxyr、2\'-dU、[3H]-Deoxyuridine、1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione、Deoxy-uridin、durd、2\'-DEOXYTHYMIDINE-5\'-DIPHOSPHATE TRISODIUM SALT

CAS号

951-78-0

分子式

C9H12N2O5

分子量

228.202

精确质量

228.075

PSA

104.55

LOGP

-1.8227

编号系统

MDL号

MFCD00006527

物化性质

外观与性状

细灰白色结晶粉末

密度

1.533 g/cm3

熔点

167-169°C(lit.)

折射率

52 ° (C=1, 1mol/L NaOH)

水溶解性

300 g/L (20 ºC)

储存条件

0-6ºC

安全信息

RTECS号

YU7490000

安全说明

S22-S24/25-S37/39

危险类别码

R36/37/38

WGK Germany

3

危险品标志

Xn

生产方法及用途

用途

是生产抗肿瘤药FUDR、抗病毒药IDUR与BrDUR的原料药,并用作生化试剂

合成路线

共找到88条合成路线 >

2'-脱氧尿苷

2'-脱氧尿苷

5-氯-2-脱氧尿嘧啶核苷

5-氯-2-脱氧尿嘧啶核苷

上游原料

共找到44个上游原料 >

1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)-uracil

1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)-uracil

C5-chloromercuri-2'-deoxyuridine

C5-chloromercuri-2'-deoxyuridine

二乙酰基-2'脱氧尿苷

二乙酰基-2'脱氧尿苷

3,3＇-二硫代二丙酸二甲酯

3,3＇-二硫代二丙酸二甲酯

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-methoxypyrimidin-2(1H)-one

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-methoxypyrimidin-2(1H)-one

3',5'-二-O-(叔-丁基二甲基硅烷基)-2’-脱氧尿苷

3',5'-二-O-(叔-丁基二甲基硅烷基)-2’-脱氧尿苷

下游产品

共找到72个下游商品 >

二乙酰基-2'脱氧尿苷

二乙酰基-2'脱氧尿苷

保护-2’-脱氧尿苷

保护-2’-脱氧尿苷

2'-deoxy-3',5'-bis-O-triphenylmethyluridine

2'-deoxy-3',5'-bis-O-triphenylmethyluridine

1,2,4-三氮唑钠

1,2,4-三氮唑钠

5'-O-三苯甲基-2'-脱氧尿苷

5'-O-三苯甲基-2'-脱氧尿苷

2'-脱氧鸟苷水合物

2'-脱氧鸟苷水合物

上游原料

1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)-uracil C5-chloromercuri-2'-deoxyuridine 二乙酰基-2'脱氧尿苷 3,3＇-二硫代二丙酸二甲酯 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-methoxypyrimidin-2(1H)-one 3',5'-二-O-(叔-丁基二甲基硅烷基)-2’-脱氧尿苷 2'-deoxy-3',5'-bis-O-triphenylmethyluridine 3',5'-O-(tetraisopropyl-disiloxane-1,3-diyl)-2'-O-phenoxythiocarbonyl-uridine 二苯二硫醚 5'-O-三苯甲基-2'-脱氧尿苷 dfC 三甲基铝 1-(O3,O5-bis-trimethylsilanyl-β-D-erythro-2-deoxy-pentofuranosyl)-5-bromo-4-trimethylsilanyloxy-1H-pyrimidin-2-one 2'-脱氧鸟苷水合物烯丙基三甲基硅烷 1-乙酰基-2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖 3',5'-O-bis-(tetrahydropyranyl)-2'-deoxyuridine 1-氯-2-脱氧-3,5-二-O-对氯苯甲酰基-D-核糖 3',5'-O-bis-(tetrahydropyranyl)-5-bromo-2'-deoxyuridine 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyuridine 尿嘧啶苯甲醇 5-甲基-2'-脱氧胞苷 O5'-acetyl-O2'-(toluene-4-sulfonyl)-uridine 2'-脱氧-5-(羟甲基)胞啶 5'-O-(tert-butyldimethylsilyl)-2'-deoxyuridine ((2R,3S,5R)-3-((4-chlorobenzoyl)oxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl 4-chlorobenzoate 3',5'-O-(1,1,3,3-四异丙基-1,3-二硅氧烷)尿苷 2’-脱氧腺苷碘苷 N,N'-Bis(trifluoroacetyl)cystamine 3',5'-Di-O-acetyl-4-O-((2,4,6-triisopropylphenyl)sulfonyl)-2'-deoxyuridine 溴脲苷二丁基二硫 [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl acetate O5'-acetyl-2'-iodo-2'-deoxy-uridine 2'-deoxy-3',5'-di-O-hexanoyluridine 3',5'-Diacetyl-4-O-(2,4,6-triisopropylphenyl)-2'-deoxyuridine 2'-脱氧肌苷 2'-脱氧胞嘧啶核苷 4-O-(2,4,6-Trimethylphenyl)-2'-deoxyuridine 1-{4-hydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydrofuran-2-yl}-1H-pyrimidine-2,4-dione 胸苷尿嘧啶核苷

下游产品

二乙酰基-2'脱氧尿苷保护-2’-脱氧尿苷 2'-deoxy-3',5'-bis-O-triphenylmethyluridine 1,2,4-三氮唑钠 5'-O-三苯甲基-2'-脱氧尿苷 2'-脱氧鸟苷水合物 E-5-(2-羰基甲氧基乙烯基)-2’-脱氧尿苷 1-[(2R,4S,5R)-5-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 2,6-二氨基嘌呤-2’-脱氧核苷 5-乙炔-2-脱氧尿苷 5-氟-2'-脱氧脲核苷 (4R,5S)-5-fluoro-3-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxohexahydropyrimidin-4-yl acetate 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione 5-氯-2-脱氧尿嘧啶核苷 5-(2-羟基乙基)-2-脱氧尿苷 3,5-双乙酰基-5-碘代-2-脱氧尿苷溴夫定 2-(hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)oxolan-3-ol (5'R)-5'-hydroxy-2',2',5',7'-tetramethylspiro[cyclopropane-1,6'-indene]-1',4'-dione 2,6-二氯嘌呤-2’-脱氧核苷 2’,3’-二脱氧尿苷 2′-氟脱氧腺苷 N6-甲基-2’-脱氧腺苷尿嘧啶 6-氯嘌呤 2’-脱氧核苷 2-deoxy-α-D-ribofuranose 1-phosphate 胸苷-d3 2’-脱氧腺苷 5-[6-(dimethylamino)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol 碘苷 N-[[(2R,3S,5R)-3-azido-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl]formamide 5'-TBDMS-2,3'-ANHYDRO-2'-DEOXYURIDINE (5S,6R)-5-fluoro-6-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione 溴脲苷乙去氧尿啶 4-ethoxy-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 三氟胸苷 1-[(2R,4S,5R)-4-叠氮基-5-(异氰基甲基)四氢呋喃-2-基]嘧啶-2,4-二酮 1-[(2R,4S,5R)-5-(azidomethyl)-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione 5-碘-2′,3′-二脱氧尿苷 8-氨基-2'-脱氧腺苷 2-脱氧-D-核糖 2'-脱氧肌苷 5-羟甲基脱氧尿苷 (5S)-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-diazinane-2,4-dione 胸苷