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植物甾醇

植物甾醇

CAS号:83-46-5
英文名:sitosterol
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化合物简介
β-谷固醇(英语:β-Sitosterol,24β-乙基胆固醇,简称为谷固醇)是化学结构与胆固醇相似的多种植物固醇中的一种。β-谷固醇是具有特异气味的白色蜡状粉末,不溶于水而溶于乙醇。
基本信息
编号系统
物化性质
安全信息
生产方法及用途
生产方法
1.取天门冬 (Aparagvs Lucidus Lindl) /3积,冷却静置过夜。收集析出物,滤液中加入2.0%热水解数小时,冷却后滤集不溶物。将此不溶物与前收集的沉淀合并,加5%加热水解,水解液以乙醚提取,回收乙醚至干,即为谷甾醇富集物。
2.由米糠油下脚提取而制得。
3. 烟草:FC,8, 32, 41, 43;BU,1;可从小麦胚芽油、玉米油中分离得到。
4. 从乙醇中得片晶。
用途
用作降血脂医药原料药。
上游原料
citrusteryl arachidate (22R)-22-hydroxy-6β-methoxy-27-nor-3α,5-cyclo-5α-cholestan-24-one Stigmasta-5,22-dien-3-ol (22S,23Z)-6β-methoxy-26-nor-3α,5-cyclo-5α-cholest-23-en-22-ol (2R,3S)-1-(2-ethyl-1,3-dithian-2-yl)-3-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethylhexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)butan-2-ol 西托糖苷 (3b)-豆甾-5-烯-3-基 beta-D-吡喃葡萄糖苷 6-(9Z)-9-十八碳烯酸酯 stigmast-5-en-3β-O-(2'-O-n-triacontanoyl)-β-D-glucopyranoside β-sitosterol 3-O-β-D-glucopyranoside β-谷甾醇乙酸酯 (3beta)-3-[(四氢-2H-吡喃-2-基)氧基]-胆-5-烯-24-醛 (24E)-(28-(2)H)ergosta-5,24(28)-dien-3β-ol (22S)-6β-methoxy-3α,5-cyclo-27-nor-5α-cholest-23-yn-22-ol (3β,22E)-Stigmasta-5,22-dien-3-yl 4-methylbenzenesulfonate 乙酸钠 (22R)-22,23-epoxy-6β-methoxy-3α,5-cyclo-5α-24-norcholane (22E,24S)-6β-methoxy-3α,5-cyclo-24-ethyl-5α-cholest-22-en-26-oic acid ethyl ester ethyl (24R)-6β-methoxy-3α,5-cyclo-5α-stigmastan-26-oate Sitoindoside I; (6'-O-棕榈酰基)-3beta-D-吡喃葡萄糖基谷甾醇 O,O'-((3R,5R,6S)-3-ethyl-6-((3S,8S,9S,10R,13S,14S,17R)-3-(methoxymethoxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptane-1,5-diyl)S,S'-dimethyl bis(carbonodithioate) (3S,8S,9S,10R,13R,14S,17R)-3-氯-17-[(2R,5R)-5-乙基-6-甲基庚烷-2-基]-10,13-二甲基-2,3,4,7,8,9,11,12,14,15,16,17-十二氢-1H-环戊二烯并[a]菲 (3R,5R,6S)-3-ethyl-6-((3S,8S,9S,10R,13S,14S,17R)-3-(methoxymethoxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptane-1,5-diol O-Methyl-22,23-dihydro-i-stigmasterin (4R,6R)-4-ethyl-6-((S)-1-((3S,8S,9S,10R,13S,14S,17R)-3-(methoxymethoxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethyl)-3-methyltetrahydro-2H-pyran-2-one (22R)-6β-methoxy-27-nor-3α,5-cyclo-5α-stigmast-24-en-26,22-lactone (4R,6R)-4-ethyl-6-((S)-1-((3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethyl)-3-methyltetrahydro-2H-pyran-2-one (3beta,5alpha,6beta,22E)-3,5-环豆甾-22-烯6-甲基醚 (2S,3R)-2-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethylhexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-5-oxoheptan-3-yl 2-bromoacetate (4R,6R)-4-ethyl-6-((S)-1-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethylhexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)ethyl)-3-methyltetrahydro-2H-pyran-2-one (4R,6R)-4-ethyl-6-((S)-1-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethylhexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)ethyl)tetrahydro-2H-pyran-2-one 6β-methoxy-3α,5-cyclo-24-nor-5α-chol-22-ene 植物甾醇 醋酸豆甾醇 (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-3-(methoxymethoxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene 24-ethylcholesta-5,Z-24(28)-dien-3β-yl acetate