百科

睾酮

CAS号：58-22-0

英文名：Testosterone

分子式

C19H28O2

熔点

152-156°C

密度

1.12 g/cm3

分子量

288.424

沸点

432.9ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

Testosterone, Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.\nTesterone is a controlled substance (anabolic steroid). Androgen.

基本信息

中文名称

睾酮

英文名称

Testosterone

中文别名

17β-羟基-4-雄甾烯-3-酮、4-雄甾烯-17β-醇-3-酮、17β-Hydroxy-3-oxo-4-androstene、17β-羟基-3-氧代-4-雄甾烯、睾丸素

英文别名

AndroGel、[14C]-Testosterone、Sustanon、Testosteron、Testim、Testoderm、(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one、Androderm、Oreton、Mertestate、17beta-hydroxy-4-androsten-3-one、Androst-4-en-3-one, 17-hydroxy-, (17β)-、[3H]-Testosterone、Andropatch

CAS号

58-22-0

分子式

C19H28O2

分子量

288.424

精确质量

288.209

PSA

37.3

LOGP

3.8792

编号系统

UNII

3XMK78S47O

物化性质

外观与性状

白色结晶无臭固体

密度

1.12 g/cm3

沸点

432.9ºC at 760mmHg

熔点

152-156°C

折射率

1.56

稳定性

Stable. Combustible. Incompatible with strong oxidizing agents.

储存条件

2-8ºC

安全信息

RTECS号

XA3030000

安全说明

S53-S45-S24/25-S36/37

危险类别码

R40

WGK Germany

3

危险品运输编码

UN 2252 3/PG 2

危险类别

4.1

包装等级

II; III

危险品标志

Xn

合成路线

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雄烯二酮

表睾酮

上游原料

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雄烯二醇

4-雄烯二醇

(+)-(1S,3aS,4S,5S,7aS)-5-acetyl-4-(2-(1,3-dioxolan-2-yl)ethyl)-3a,4,5,6,7,7a-hexahydro-7a-methyl-1-t-butoxyindan

(+)-(1S,3aS,4S,5S,7aS)-5-acetyl-4-(2-(1,3-dioxolan-2-yl)ethyl)-3a,4,5,6,7,7a-hexahydro-7a-methyl-1-t-butoxyindan

(+)-(1S,3aS,4S,5S,7aS)-1-t-Butoxy-3a,4,5,6,7,7a-hexahydro-4-(3-hydroxypropyl)-5-i-propenyl-7a-methylindane

(+)-(1S,3aS,4S,5S,7aS)-1-t-Butoxy-3a,4,5,6,7,7a-hexahydro-4-(3-hydroxypropyl)-5-i-propenyl-7a-methylindane

(+)-(5aS,5bS,8S,8aS,10aS,10bR)-8-t-Butoxy-des-A-androstano(5,10-c)isoxazole

(+)-(5aS,5bS,8S,8aS,10aS,10bR)-8-t-Butoxy-des-A-androstano(5,10-c)isoxazole

下游产品

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(8S,9R,10S,13S,14S,17S)-9,17-dihydroxy-10,13-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one

(8S,9R,10S,13S,14S,17S)-9,17-dihydroxy-10,13-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one

17β-hydroxyandrostan-3-one

17β-hydroxyandrostan-3-one

5a-雄甾烷-3a,17b-二醇

5a-雄甾烷-3a,17b-二醇

4-雄烯二醇

16β-Hydroxytestosterone

16β-Hydroxytestosterone

上游原料

雄烯二醇 4-雄烯二醇睾酮 (+)-(1S,3aS,4S,5S,7aS)-5-acetyl-4-(2-(1,3-dioxolan-2-yl)ethyl)-3a,4,5,6,7,7a-hexahydro-7a-methyl-1-t-butoxyindan (+)-(1S,3aS,4S,5S,7aS)-1-t-Butoxy-3a,4,5,6,7,7a-hexahydro-4-(3-hydroxypropyl)-5-i-propenyl-7a-methylindane (+)-(5aS,5bS,8S,8aS,10aS,10bR)-8-t-Butoxy-des-A-androstano(5,10-c)isoxazole (+)-(1S,3aS,4S,5S,7aS)-5-Acetyl-1-t-butoxy-4-(3-t-butyldimethylsiloxypropyl)-3a,4,5,6,7,7a-hexahydro-7a-methylindane (1S,3aS,4S,5S,7aS)-4-(2-(1,3-dioxolan-2-yl)ethyl)-3a,4,5,6,7,7a-hexahydro-5-(1-hydroxy-1-methylethyl)-7a-methyl-1-t-butoxyindan 17β-methoxy-4-androsten-3-one (3S,4R,8R,9S,10R,13S,14S,17S)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,4,17-triol 17Alpha-羟基黄体酮 (+)-(8R,9S,10R,13S,14S,17S)-17-t-Butoxy-4-androsten-3-one 3-cycloethylenedioxy-17β-O-(tetrahydropyranyl)-androst-5-ene (17β)-androst-4-en-17-yl acetate 1-((1S,3aS,4R,7aS)-4-(2-(1,3-dioxolan-2-yl)ethyl)-1-(tert-butoxy)-7a-methyloctahydro-1H-inden-5-yl)ethanol (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-17-((tetrahydro-2H-pyran-2-yl)oxy)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one 3,3-(ethylenedioxy)-5-androsten-17β-ol 孕烯醇酮 (1S,3aS,4R,5S,7aS)-4-(2-(1,3-dithiolan-2-yl)ethyl)-3a,4,5,6,7,7a-hexahydro-5-isopropenyl-7a-methylindan-1-ol (1S,7AS)-1-tert-butoxy-7a-methyl-5,6,7,7a-tetrahydroindan-5-one 雄烯二酮 (1S,3aS,4R,5S,7aS)-4-(2-formylethyl)-3a,4,5,6,7,7a-hexahydro-5-isopropenyl-1-methoxymethoxy-7a-methylindan 4-androstane-3β,17β-diol 16beta-(Phenylseleno)progesterone 黄体酮 (+)-(8S,9S,10S,13S,14S,17S)-17-t-Butoxy-10-(3-oxo-1-butenyl)-5-oxo-des-A-androstane 17|A-Hydroxy-5-oxo-A-nor-3,5-secoandrostan-3-oic Acid 乙硫醇 (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-17-((triethylsilyl)oxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (+)-(1S,3aS,4S,5S,7aS)-1-t-Butoxy-4-(3-t-butyldimethylsiloxypropyl)-3a,4,5,6,7,7a-hexahydro-5-isopropenyl-7a-methylindane (+)-(1S,3aS,4S,7aS)-1-t-Butoxy-4-(3-t-butyldimethylsiloxypropyl)-3a,4,7,7a-tetrahydro-7a-methylindan-5(6H)-one 3-oxo-androst-4-en-17β-yl Se-phenyl selenocarbonate (10R,13S,17S)-10,13-dimethyl-17-((tetrahydrofuran-2-yl)oxy)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (+)-(1S,7aS)-1-t-Butoxy-4-(3-t-butyldimethylsiloxypropyl)-7,7a-dihydro-7a-methylindan-5(6H)-one (3b,17b)-雄甾-5-烯-3,17-二醇 3,17-二乙酸酯 (-)-(8S,9S,10S,13S,14S,17S)-17-t-Butoxy-10-formyl-5-oxo-des-A-androstane androst-5-ene-17-one-3-ethylene ketal (8R,9S,10R,13S,14S,17S)-3-(ethylthio)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol 醋酸睾酮 (8R,9S,10R,13S,14S,17S)-6-(1,3-dithian-2-yl)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one 4,5-环氧-17beta-羟基-5-雄甾烷-3-酮 17β-(methoxymethoxy)androst-4-en-3-one (+)-(1S,3aS,4R,5S,7aS)-4-(2-(1,3-dioxolan-2-yl)ethyl)-3a,4,5,6,7,7a-hexahydro-5-isopropenyl-7a-methyl-1-t-butoxyindan (1S,3aS,4R,5S,7aS)-4-(2-(1,3-dithiolan-2-yl)ethyl)-3a,4,5,6,7,7a-hexahydro-5-isopropenyl-1-methoxymethoxy-7a-methylindan (+)-(8S,9S,10S,13S,14S,17S)-17-t-Butoxy-10-hydroxymethyl-5-oxo-des-A-androstane 17β-TBDMS-testosterone 去氢表雄酮

下游产品

(8S,9R,10S,13S,14S,17S)-9,17-dihydroxy-10,13-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one 17β-hydroxyandrostan-3-one 5a-雄甾烷-3a,17b-二醇睾酮 4-雄烯二醇 16β-Hydroxytestosterone 三苯基氢化锡 2-Alpha-羟基睾酮 Etiocholandiol 4-羟基-睾酮环戊丙酸睾酮睾酮癸酸酯表雄酮雌酚酮 6alpha-羟基-雄甾-4-烯-3,17-二酮福美司坦 4-雄甾烯-3,17-二醇雄烯二酮表睾酮 15α-hydroxy-4-androsten-3,17-dione 苯乙酸睾酮 7-羟基睾酮 (17beta)-17-羟基雄甾-4-烯-3,6-二酮雄甾-1,4-二烯-3,17-二酮丙酸睾酮 17Beta-羟基-4-雄烯-3-酮 3-[邻羧基甲基]肟还原胆烷醇酮 17|A-Hydroxy-5-oxo-A-nor-3,5-secoandrostan-3-oic Acid 睾内酯 5-雄甾-3-烯-17-酮 6,17-二羟基-6b,17b-雄甾-4-烯-3-酮 5α-二氢睾酮雄甾-4-烯-3β,6β,17β-三醇 17β-hydroxy-4α,5-epoxy-5α-androstan-3-one 5alpha-雄烷二醇 5a-雄甾烷二酮 (6S,8R,9S,10R,13S,14S)-6-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione 宝丹酮 6alpha-羟基睾酮本胆烷-17β-醇-3-酮 14,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one (15a,17b)-15,17-二羟基-雄甾-4-烯-3-酮 (8R,9S,10R,13S,14S,17S)-10,13-二甲基-3-亚甲基-1,2,6,7,8,9,11,12,14,15,16,17-十二氢环戊烯并[a]菲-17-醇屈他雄酮 19-羟基睾酮庚酸睾酮雄酮